消化系统恶性肿瘤证候的研究进展

Abstract

恶性肿瘤是我国高致死率的疾病之一，而所有肿瘤中，消化系统恶性肿瘤占到了约60%~70%。证候是中医对疾病认识、临床诊疗和疗效评价的核心基础，有效的中医治疗有赖于正确的辨证。本文综述了胃癌、食管癌、结直肠癌、肝癌、胰腺癌五种消化系统恶性肿瘤的证候分布、证候动态变化、证候生物学基础、证候形成和演变的分子机制以及辨证治疗等研究进展，并展望证候研究的挑战和发展，为临床消化系统恶性肿瘤的中医诊断和治疗提供参考。 Malignant tumor is one of the high mortality rates in diseases. Among all the digestive systems, ma-lignant tumor accounts for about 60%~70% of all cancer pathogenesis. ZHENG, also called Tradi-tional Chinese medicine (TCM) syndrome is the core basis of understanding disease, clinical diagno-sis and treatment and curative effect evaluation, and effective treatment depends on the correct ZHENG differentiation in TCM. This paper reviews ZHENG’s distribution, dynamic changes, biological basis, molecular mechanism and research progress of ZHENG formation and evolution, and ZHENG- based diagnosis and treatment in stomach cancer, esophageal cancer, colorectal cancer, liver cancer and pancreatic cancer, five kinds of digestive system malignant tumor, looking to the challenge and development of the ZHENG researches, and providing reference for clinical diagnosis and treatment of TCM in the digestive system malignant tumor.