勤労中年男性の血清脂質に及ぼす喫煙習慣の影響

Abstract

The purpose of this study was to examine the effects of smoking habits on serum lipids in middle-aged male workers considering the effect of body mass index which would be decreased by habitual smoking. The subjects were 1431 middle-aged men who worked at a enterprise in Hiroshima prefecture. The effects of habitual smoking on serum lipids were evaluated by two models of analysis of covariance (PC-SAS: GLM procedure) involving several confounding factors. Model 1 involved such confounding factors as body mass index, age, drinking habits, physical activity, working system and type of job, and model 2 involved the confounding factors except body mass index in model 1. In model 1 the effect of body mass index is adjusted, and in model 2 the effect of body mass index is reflected in the results of analysis. The main results are summerized as follows: 1) On the whole, smokers indicated lower body mass index than non-smokers. 2) Smokers indicated lower HDLC level and higher atherogenic index than non-smokers. This means that smokers have higher risk of arteriosclerotic disease than non-smokers. 3) Lower body mass index in smokers had no benefical effects for their serum lipids.