Abstract
Radial bone mineral content (BMC) was measured by 125-I single photonabsorptiometry in patients with prostatic cancer and benign prostatic hypertrophy. The correlations between radial BMC and serum Ca, Pi and alkaline phosphatase were also investigated from the standpoint of bone metabolism. A slight increase of radial BMC was demonstrated in patients with prostatic cancer as well as prostatic hypertrophy, suggesting the existence of a prostatic osteoblast stimulating factor in the patients with prostatic tumors. But regarding the effect of bone metastasis of prostatic cancer on radial BMC, no significant increase in radial BMC was indicated in the patients with bone metastasis. Serum levels of total Ca and inorganic phosphorous were slightly lower in prostatic cancer than in benign prostatic hypertrophy. No changes of radial BMC and serum Ca and Pi levels were demonstrated after orhiectomy and hormonal theraphy.
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