Abstract

We investigated the clinical results of 73 patients who had tracheal invasion of thyroid carcinoma (papillory carcinoma and folliculor carcinoma) and received surgical treatment between 1978 and 2003 at Kurume University Hospital. The 10-year local control rate was 95% in the patients without tracheal invasion and 74% in those with tracheal invasion. There was a significant difference between the two groups (p<1%). Extensive resection of the trachea was performed in 37 out of the 73 patients. In 33 patients, the defect in the tracheal wall was reconstructed secondarily using a local flap such as the nasal septum cartilage or hydroxylapatite. An end-to-end anastomosis was performed in four patients with extensive invasion to the membranous portion of the trachea. End-to-end anastomosis is the most effective, physiological method of reconstructing the airway because of its full diameter and mucociliary function.

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