Abstract
An 82-year-old woman, having a pinkish nodule on her left nasolabial area, visited our clinic. Total excision was performed, and then reconstructed by Abbe flap. Histopathologically, the tumor had two characteristic areas. Basaloid cells with cribriform pattern proliferated in the major portion of the tumor, in which peripheral palisading, clefts and follicular differentiated horn cysts were seen. Another portion in the tumor showed small solid aggregations, in which hair germ-like structures were budding and some of them were surrounded by a thick rim of homogeneous, eosinophilic basement membrane-like materials. No tubular differentiation was seen. Keratin 15, keratin 20, CD 34, S-100 protein, or CEA were not demonstrated immunohistochemically in the tumor cells. Finally, we diagnosed this tumor as nodular-cystic basal cell carcinoma. [Skin Cancer (Japan) 2002; 17: 254-258]
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