Abstract

We describe a case of uterine leiomyosarcoma associated with acute infection. A 56-year-old woman presented with atypical genital bleeding. Endometrial cytology revealed isolated bizarre spindle-shaped or fibrous cells. The cytological diagnosis was malignant mesenchymal tumor (probably uterine leiomyosarcoma). She underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy. Macroscopically, the intramural tumor showed massive hemorrhagic areas and necrosis. Histologically, the tumor showed smooth muscle differentiation with marked cytologic atypia and increase in mitotic figures, and the diagnosis was leiomyosarcoma.

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