ダイナミックＭＲＩにおける舌へん平上皮癌の信号増強効果発現パターンの定量的評価

Abstract

Dynamic enhanced magnetic resonance (MR) images of 22 tongue squamous cell carcinomas (T2: 9 cases, T3: 7 cases, T4: 6 cases) were analyzed quantitatively. These tumors showed peripheral enhancement patterns. Enhancement patterns were compared between central and peripheral regions. Signal enhancement to noise ratios (SE/N) of the regions of interest (ROIs) located in the peripheral and central regions of the tumor were measured. In addition, maximum SE/N, the time of maximum SE/N, %-washout, and increase rate of SE/N were calculated. On the basis of tumor size and histopathological features, images were divided into the following groups: T2 group, T3 group, and T4 group, Grade 1 and 2 group (L-Gr.), and Grade 3 (H-Gr.) group. The variables described above were compared among the groups.There were no statistically significant differences in maximum SE/N, time of maximum SE/N, or increase rate of SE/N among different tumor sizes. However, %-washout of the central region in the T2 group was lower than that in the T3 group. Although there was no distinct trend in the peripheral region, T3 and T4 tumors tended to have a poorer supply of contrast medium in the central region.Histopathologically, low-grade tumors tended to show early enhancement in the peripheral region. However, in the central region, low-grade tumors showed a poorer supply of contrast medium.Our results suggest that clinicopathological features correlate with enhancement patterns on dynamic MR images of tongue squamous cell carcinomas.