咽喉頭異常におけるスルピリドの使用経験

Abstract

The effect of the anti-depressant: Sulpiride on pharyngolaryngeal abnormal sensation was evaluated in 50 patients treated for 4 weeks. The depressive state of the patients was evaluated by the Self-Rating Questionnaire for Depression (SRQ D). 1) Depression was noted in 12 of the patients (24%). 2) Sulpiride improved the SRQ D scores of 70% of the depressed patients and of 36.8% of the non-depressed patients. 3) However, subjective symptoms were reduced in 84.2 % of the non-depressed patients and in 60% of the depressed patients. 4) Mild side-effects were noted in 4 patients (8%) during administration of this drug.