Abstract
Malignant myoepithelioma was found in the nasal cavity of a 66-year-old woman who presented with a rapidly expanding tumor accompanied by episodes of epistaxis. The tumor was removed by an extended Denker's operation and studied by light and electron microscopy, including immunohistochemical staining. By light microscopy, the tumor appeared to be a poorly differentiated epithelial neoplasm of undetermined origin; however, immunohistochemical examination showed myoepithelial differentiation with malignant potential, indicative of a nasal gland origin. To our knowledge, this is the first case of malignant myoepithelioma of the nasal cavity to be reported.
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