Abstract

The effects of chenodeoxycholic acid (CDCA) and ursodeoxycholic acid (UDCA) on enzymic activity of lipase, as well as the relationship between the lipase activity and the concentration of bile acids in bile, were studied. In the presence of bile administered CDCA, the lipase activity was enhanced significantly. A correlation between the lipase activity and the common logarithm of the concentration of total bile acid and CDCA in bile was observed, correlation coefficients being 0.723 (n=30) and 0.732 (n=30), respectively. In addition, it was observed from the result of multiple regression that CDCA and UDCA increased the lipase activity.

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