Abstract

Metastasis in the thyroid gland (MT) is clinically rare, although it is increasing in number. We report three cases of MT. All cases showed a rapidly-growing mass in the neck, and were diagnosed by fine-needle aspiration biopsy. The first case was a 63-year-old man who had been treated for hepatocellular carcinoma (HCC) with chemotherapy and interferon for one year. MT was treated by thyroidectomy. He died due to primary recurrence 2 years later, but had remained free of recurrence in the neck. The second case was a 48-year-old woman, who complained of dysphagia and dyspnea. One year earlier, she had received postoperative chemotherapy for breast cancer. She underwent total thyroidectmy and died six months later due to generalized metastasis from breast cancer. There was no local recurrence in the neck. The third case was a 60-year-old woman, who had been diagnosed colon cancer three years earlier, and had been treated by a surgical resection and chemotherapy. She had also been treated for lung metastasis. MT was found after detection of brain metastasis. She underwent thyroidectomy. After the procedure, she was transferred to another hospital for additional chemotherapy and was lost to follow-up.

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