Abstract
We describe a 46-year-old man with T 4 N 2 bM 0 squamous cell cancer of the floor of the mouth. After concomitant radiotherapy (51.2Gy) and chemotherapy (CBDCA 480mg), he underwent total glossolaryngectomy, bilateral neck dissection, and reconstruction using a free rectus abdominis flap. Postoperatively, an IVH catheter was placed, and antibiotics (CEZ) were given prophylactically. Candida albicans sepsis developed 3 weeks after the operation. Administration of FCZ 200 mg daily for 17 days improved sepsis; however, candida osteomyelitis developed in the ribs and lumbar vertebrae 4 months after the operation. Persistent osteomyelitis of the ribs required partial costectomy. Postoperatively, the patient received FCZ 200 mg daily for 1 month, followed by FCZ 100mg daily. Osteomyelitis of the ribs completely healed, but the lesions of the lumbar vertebrae were not controlled.
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