Abstract

In order to obtain a biocompatibility of an alumina (Al2O3) ceramics, a hydroxyapatite (HAp) layer on the surface has been formed by KrF excimer laser irradiation. The biocompatibility of HAp/Al2O3 composite material has been confirmed in vitro. An apatite-wollastonite glass (A-W glass) and a simulated body fluid (SBF) have been used as a substitute of a bone and a human blood plasma, respectively. The HAp/Al2O3 sample which is faced to A-W glass was immersed into SBF keeping at 36.5°C and pH 7.2. In the case of sample immersed for 2 weeks, morphological change on the HAp/Al2O3, surface was observed by an electron probe microanalyzer (EPMA). An X-ray diffraction (XRD) pattern was indicated that a bone-like apatite was formed on the HAp/Al2O3 surface. From these results, it is considered that HAp/Al2O3, composite material formed by KrF excimer laser irradiation has a good biocompatibility.

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