Abstract

A fibrin adhesive agent consists of clotting factors and is applied for tissus adhesion in surgery. We used it for two cases with delayed wound-healing. Case 1 was a 56-year-old-male with diabetic gangrene. After right Syme amputation, wound-healing was delayed. Case 2 was a 48-year-old-female with spinal cord injury. After rotation flap for decubitus in her sacral region, wound-healing was delayed. In both cases, suturing was tried several times but failed, so a fibrin adhesive agent was injectet into the wound and applied to the wound after suturing. Using this fibrin adhesive agent wound-healing was successful. In this case wound-healing appeared to be due to the useful action—adhesion, fixation, filling, hemostasis, etc—of a fibrin adhesive agent based. A fibring adhesive agent is safe and will be used more clinically in the future.

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