Abstract
Blood gases of platelet concentrates (PC) were measured at 37°C by means of a pH/gas analyzer. About 19ml of PC were stored in a 150ml storage bag made of polyvinyl chloride with flat-bed agitation at 22°C for up to 3 days. PC pH fall was roughly proportional to the platelet count, in which the CO2 tension was inversely associated with the O2 tension. Rates of pH fall were due to not only lactate generation by platelet anerobic glycolysis but an increase in CO2 tension. The relationship between PC pH and the platelet count was maintained during 3-day storage, although the CO2 tension but not the O2 tension decreased significantly on day 3 with increasing production rates of lactate. The present results indicate that PC with a higher platelet count become acidified during storage, and one beneficial way to prevent this pH fall is solely to lower the platelet concentration in the storage bag.
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