Abstract
In the title compound, C31H32BrN3O3, the morpholine ring adopts a chair conformation, and the planar quinoline system is twisted with respect to the phenyl rings, with dihedral angles of 17.6 (4) and 75.1 (3)°. Intramolecular C—H⋯O and C—H⋯N hydrogen bonds are present. The crystal packing is stabilized by weak C—H⋯O hydrogen bonding and C—H⋯π interactions.
Highlights
C31H32BrN3O3, the morpholine ring adopts a chair conformation, and the planar quinoline system is twisted with respect to the phenyl rings, with dihedral angles of 17.6 (4) and 75.1 (3)
The crystal packing is stabilized by weak C—HÁ Á ÁO hydrogen bonding and C— HÁ Á Á interactions
Symmetry codes: (i) x−1, y, z; (ii) x, y, z+1; (iii) x+1, y, z
Summary
Key indicators: single-crystal X-ray study; T = 298 K; mean (C–C) = 0.011 A; R factor = 0.076; wR factor = 0.236; data-to-parameter ratio = 11.0. Intramolecular C—HÁ Á ÁO and C— HÁ Á ÁN hydrogen bonds are present. The crystal packing is stabilized by weak C—HÁ Á ÁO hydrogen bonding and C— HÁ Á Á interactions. Related literature For the synthesis of other phamaceutically active derivatives through conventional and other synthetic routes, see: Andries et al (2005); Gaurrand et al (2006); Mao et al (2007); Dalla Via et al (2008). See: Petit et al (2007); Rahmani et al (2009)
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