Abstract
The main molecule of the title dimethylformamide monosolvate, C28H20BrN7O2S·C3H7NO, comprises bromophenyl (A), thiadiazolyl (B), pyrazolyl (C), phenyl (D) and indolyl (E) ring systems with twist angles between the planes through neigbouring rings A/B, B/C, C/D and C/E of 33.7 (1), 14.8 (1), 60.7 (2) and 20.9 (1)°, respectively. In the crystal, the molecules are related by c-glide symmetry to form columns parallel to [001] which are linked by intermolecular N—H...O, C—H...O and C—H...Br contacts.
Highlights
The molecules are related by c-glide symmetry to form columns parallel to [001] which are linked by intermolecular N—HÁ Á ÁO, C—HÁ Á ÁO and C—HÁ Á ÁBr contacts
1H-Pyrazole-3-carbohydrazides have been used in the synthesis of anti-nociceptive, antiinflammatory and antipyretic agents (Malvar et al, 2014)
Are related by c-glide symmetry to form columns parallel to [001] which are linked by intermolecular N—HÁ Á ÁO, C— HÁ Á ÁO and C—HÁ Á ÁBr contacts (Table 1, Fig. 2)
Summary
1H-Pyrazole-3-carbohydrazides have been used in the synthesis of anti-nociceptive, antiinflammatory and antipyretic agents (Malvar et al, 2014). 1,3,4-thiadiazoles have different biological activities and can be used as anticancer, diuretic, antibacterial, antifungal, antitubercular and leishmanicidal agents (Dawood & Farghaly, 2017; Li et al, 2013; Lv et al, 2018; Serban et al, 2018). In the main molecule of the title compound (Fig. 1), the angles between planes of the bromophenyl (A), thiadiazolyl (B), pyrazolyl (C), phenyl (D) and indolyl (E) rings A/B, B/C, C/D and C/E are 33.7 (1), 14.8 (1), 60.7 (2) and 20.9 (1) respectively.
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