N-(3-Oxo-2-phenyl-2,3-dihydro-1H-pyrrolo[1,2-c]imidazol-1-yl)-N′-phenyl-N-(2,4,6-trimethylphenyl)urea ethyl acetate solvate

Abstract

The title compound, C28H26N4O2·C4H8O2, was prepared from (2,4,6-trimethyl­phen­yl)(1H-pyrrol-2-ylmethyl­ene)amine and phenyl isocyanate in the presence of catalytic amounts of [Pd(PPh3)4]. Recrystallization of the crude product from a penta­ne–ethyl acetate mixture (10:1) yielded the title compound as the ethyl acetate solvate. The pyrrolo[1,2-c]imidazole core is essentially planar. In addition, a new stereogenic center at the ring C atom of the biheterocyclic group attached to the urea N atom has been formed during the reaction sequence. The crystal structure is influenced by various N—H⋯O and C—H⋯O hydrogen bonds.