Abstract
In the title compound, C16H14N2O2, the conformation about the C=C bond is E, and the two amide groups are effectively orthogonal [the C—N—N—C torsion angle is 104.5 (2)°]. In the crystal structure, the amide groups groups associate via N–H⋯O hydrogen bonding, forming supramolecular tapes with undulating topology along the c-axis direction.
Highlights
In the title compound, C16H14N2O2, the conformation about the C C bond is E, and the two amide groups are effectively orthogonal [the C—N—N—C torsion angle is 104.5 (2) ]
For recent studies directed towards developing drugs for the treatment of tuberculosis, see: Carvalho et al (2008)
R-factors based on F2 are statistically about twice as large as those based on F, and R- factors based on ALL data will be even larger
Summary
Carvalho,a,b Edson F. da Silva,b Edward R. Wardelle a Instituto de Quımica, Universidade Federal do Rio de Janeiro, 21949-900, Rio de Janeiro, RJ, Brazil, bDepartamento de Sıntese Orgánica, Instituto de Tecnologia em Fármacos FIOCRUZ, Manguinhos, Rua Sizenando Nabuco 100, Manguinhos, 21041-250, Rio de Janeiro, RJ, Brazil, cDepartment of Chemistry, University of Malaya, 50603 Kuala Lumpur, Malaysia, dCentro de Desenvolvimento Tecnológico em Saúde (CDTS), Fundação Oswaldo Cruz (FIOCRUZ), Casa Amarela, Campus de Manguinhos, Av. Brasil 4365, 21040-900, Rio de Janeiro, RJ, Brazil, and e. C16H14N2O2, the conformation about the C C bond is E, and the two amide groups are effectively orthogonal [the C—N—N—C torsion angle is 104.5 (2) ]. The amide groups groups associate via N–. H O hydrogen bonding, forming supramolecular tapes with undulating topology along the c-axis direction
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