Abstract

Recent clinical evidence suggests efficacy of a traditional medicinal product containing the combination of myrrh (Commiphora myrrha (Nees) Engl.), coffee charcoal (Coffea arabica L.) and chamomile flower dry extract (Matricaria chamomilla L.) for the treatment of diarrhea and irritable bowel syndrome (IBS) [1]. Mast cells seem to play a key role in IBS symptom generation as recent studies show an increased activation and degranulation rate of mucosal mast cells in the intestinal tissue of IBS patients.

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