Myristica fragrans Derived Phytochemicals against Shikimate Dehydrogenase of E. coli Causing Diarrhea

Abstract

Medicinal plants play a key role in human health care. Phytochemicals can be derived from different parts of plants. Different medicinal plants and their phytoextracts have shown anti-microbial action. Phytochemicals from Myristica fragrans plant extract are traditionally used to cure Diarrhea. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that Eugenol can effectively deactivate the shikimate dehydrogenase enzyme thereby interrupting the life cycle of the organism.