Abstract
To date, there is no consensus on the question of which tissues are more appropriate to use for tympanic membrane plastic surgery. We decided to study the use of xenograft from sheep pericardium in myringoplasty in rabbits in the experiment, and in patients with chronic dry mesotympanitis. Experimental morphological studies using a xenograft were carried out in 28 rabbits. In the experiment, a positive result was obtained in 25 (89.3%) rabbits. In addition, 77 patients with dry perforation of the tympanic membrane were examined. To compare the results of the study, these patients underwent myringoplasty: 54 patients with the use of a xenograft from the sheep pericardium, 23 patients with the use of the fascia of the temporal muscle. Reliable engraftment of a xenograft from sheep pericardium after surgery was observed in 48 patients (88.9%), and with the use of temporal muscle fascia in 20 patients (86.9%).
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