Myricetin 5,7,3′,4′,5′-pentamethyl ether and other methylated flavonoids from Murraya paniculata

Abstract

Seven flavonoids, including one new flavonol, were isolated from the leaves of Murraya paniculata (Rutaceae). Four were identified as previously known constituents of M. paniculata or allied species, namely, 5,7,3′,4′,5′-pentamethoxyflavone, 5,7,8,3′,4′,5′-hexamethoxyflavone, 3,5,7,3′,4′,5′-hexamethoxyflavone and 3,5,7,8,3′,4′,5′-heptamethoxyflavone. The structure of the new flavonol was elucidated as 3-hydroxy-5,7,3′,4′,5′-pentamethoxyflavone on the basis of spectroscopic studies. Two other flavonoids, a methylated flavanone and its corresponding chalcone isomer were identified as 2-( S)-5,7,3′,4′,5′-pentamethoxyflavanone and 2′-hydroxy-3,4,5,4′,6′-pentamethoxychalcone, respectively.