Myoinositol In Restoring Spontaneous Ovarian Activity in Patients with Polycystic Ovarian Syndrome (PCOS)

Abstract

Objective: To assess the efficacy of myoinositol in the management of patients with Polycystic ovarian syndrome (PCOS) Methods: It was quasi experimental study conducted inDepartment of Obstetrics and Gynecology Services institute of Medical Sciences, Services Hospital, Lahore from 30-6-2018 to 31-12-2018. 140 sub fertile patients with PCOS were selected through random sampling. Patients were given 2gram of myoinositol/day. The effect was assessed after 3 and 6 months of treatment by monthly menstrual cycle regularity and ovulation. All this information was recorded in proforma. Results: The mean age of patients was 26.90±5.52years. The mean BMI of patients was 37.38±4.08kg/m2. After 3 months of treatment, menstrual cycle become regular in 34 (24.3%) patients and ovulation occurred in 54 (38.6%) cases. After 6 months of treatment, menstrual cycle become regular in 75 (53.6%) patients and ovulation occurred in 101 (72.1%) cases. Conclusion: The myoinositol is an effective treatment in terms of regularity of menstrual cycle and ovulation induction in subfertile women with PCOS. Keywords: Myoinositol, Polycystic ovarian syndrome, Menstrual irregularity, Ovulation