Abstract
Background A critical stage in the quantification of myocardial strain from raw cine DENSE images is the transformation of Eulerian to Lagrangian displacement. Eulerian displacement, directly measured by DENSE, indicates the prior location of a myocardial element. Lagrangian displacement, generally easier to interpret by cardiologists and radiologists, tracks a myocardial element forward in time. Estimating Lagrangian displacement proves challenging, given the non-uniformly spaced displacement origins and the possibly low signal-to-noise ratio (SNR) of the Eulerian data. In this study, we investigated using the TPAS to accurately estimate myocardial strain from raw DENSE displacement fields.
Highlights
A critical stage in the quantification of myocardial strain from raw cine displacement encoding with stimulated echoes (DENSE) images is the transformation of Eulerian to Lagrangian displacement
Cine DENSE images were acquired in normal volunteers and patients with heart disease using a 1.5 T MR system (Avanto, Siemens), after informed consent and in accordance with protocols approved by our Institutional Review Board
To validate the thin plate spline technique, radial and circumferential strain data were estimated from cine DENSE images using both the conventional and thin-plate approximating spline (TPAS) analyses
Summary
To improve the estimation of myocardial strain from cine displacement encoding with stimulated echoes (DENSE) images using the thin-plate approximating spline (TPAS). Energy and the distance to the deformation data. The TPAS requires only a single parameter constraining the allowable displacement approximation error.
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