Abstract
Background Cardiac involvement of patients with systemic lupus erythematosus (SLE) is one of the main complications contributing to morbidity and mortality, however a significant portion of patients presents with subclinical disease. Non-invasive contrast-enhanced cardiovascular magnetic resonance (CMR) imaging is a well-established diagnostic tool to identify myocardial tissue alterations and morphological and functional changes. In this study, we aimed to assess cardiac abnormalities in SLE patients using LGE-CMR and, furthermore, the relation of serological inflammatory biomarkers to the cardiac LGE-CMR findings.
Highlights
Cardiac involvement of patients with systemic lupus erythematosus (SLE) is one of the main complications contributing to morbidity and mortality, a significant portion of patients presents with subclinical disease
We studied 27 SLE patients (24 females, 45 ± 13 years) and 30 healthy age-matched volunteers who served as a control group (27 females, 44 ± 11 years)
The presence of LGE was associated with CRP levels higher than 2 mg/l (p = 0,03), independent of the pattern of cardiac involvement (Table 1)
Summary
Cardiac involvement of patients with systemic lupus erythematosus (SLE) is one of the main complications contributing to morbidity and mortality, a significant portion of patients presents with subclinical disease. We aimed to assess cardiac abnormalities in SLE patients using LGE-CMR and, the relation of serological inflammatory biomarkers to the cardiac LGE-CMR findings
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