Myocardial Infarction in a Young Female with Palindromic Rheumatism: A Consequence of Negative Remodeling

Timothy R Larsen,Shukri David,Jamal Zarghami,Sachin Kumar Amruthlal Jain

doi:10.1155/2012/924141

Abstract

Palindromic rheumatism is a rare disease associated with systemic inflammation. Negative or constrictive coronary artery remodeling is typically not seen until the 7th or 8th decade of life. We report a case of a young female with palindromic rheumatism who suffered a non-ST segment elevation myocardial infarction secondary to a flow-limiting lesion that demonstrated negative remodeling by intravascular ultrasound (IVUS).

Highlights

Palindromic rheumatism is a rare form of inflammatory arthritis characterized by sudden attacks of painful inflammation in one or multiple joints
The disease is associated with several markers of systemic inflammation including C-reactive protein, rheumatoid factor, and prolonged erythrocyte sedimentation rate [2]
She admitted to having similar episodes over the previous month that were less severe, which she assumed were “attacks of pleuritis.”. These episodes were provoked by exertion and relieved by rest. Her medical history was significant for palindromic rheumatism diagnosed three years ago; laboratory results from approximately four months prior to presentation showed C-reactive protein of 19 mg/L and erythrocyte sedimentation rate of 40 mm/hour

Summary

Introduction

Palindromic rheumatism is a rare form of inflammatory arthritis characterized by sudden attacks of painful inflammation in one or multiple joints. The attacks last for hours to days and resolve as quickly as they begin [1]. The disease is associated with several markers of systemic inflammation including C-reactive protein, rheumatoid factor, and prolonged erythrocyte sedimentation rate [2]. The chronic inflammatory state associated with this condition can result in unusual presentations of common diseases

Case Presentation

Discussion

Findings

Conclusion