Abstract
IN 1836 Jean Bouillaud first called attention to the relationship of acute generalized febrile articular rheumatism to disease of the heart. 1 In 1881, Charcot argued, have collected a considerable number of cases in which endocarditis has developed in chronic rheumatism without the disease ever having assumed an acute form. 1 In 1876, Sir Alfred Garrod said that he had never met with an instance in which I could trace the occurrence of pericarditis or endocarditis to rheumatoid arthritic disease, however acute the joint infection may have been and I am of the opinion that this absence of cardiac inflammation is one of the best tests for distinguishing this malady from genuine rheumatism. 1 The consensus that heart disease was a manifestation of rheumatic fever and not of rheumatoid arthritis persisted until Baggenstoss and Rosenberg reported on the cardiac lesions at autopsy in 20 cases of infectious arthritis. 2
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