Abstract

Pulmonary hypertension (PH) leads to progressive right ventricular (RV) dilatation, hypertrophy, and systolic dysfunction. PH is also associated with the presence of late gadolinium enhancement in the interventricular septum (IVS). Post-contrast T1 mapping is a previously validated non-invasive technique for the quantification of extracellular volume increase as a surrogate of diffuse interstitial fibrosis. The aim of our study was to evaluate the presence of septal fibrosis in PH patients with T1 mapping, and to investigate potential correlations with RV performance and hemodynamic status. Methods

Highlights

  • Pulmonary hypertension (PH) leads to progressive right ventricular (RV) dilatation, hypertrophy, and systolic dysfunction

  • PH is associated with the presence of late gadolinium enhancement in the interventricular septum (IVS)

  • The aim of our study was to evaluate the presence of septal fibrosis in PH patients with T1 mapping, and to investigate potential correlations with RV performance and hemodynamic status

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Summary

Open Access

Myocardial fibrosis with T1 mapping and right ventricular performance in pulmonary hypertension. Ines Garcia-Lunar*, Pablo Pazos, Eduardo Pozo, Claudia Calcagno, Sarayu Ramachandran, Charles M Adapoe, Ajith Nair, Adam Jacobi, Valentin Fuster, Javier Sanz. From 16th Annual SCMR Scientific Sessions San Francisco, CA, USA. From 16th Annual SCMR Scientific Sessions San Francisco, CA, USA. 31 January - 3 February 2013

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