Abstract
Cardiac involvement is a major risk factor for sudden death in patients with systemic sarcoidosis. Pathologically, cardiac sarcoid lesions can be classified as early (mainly lymphocytic, similar to lymphocytic myocarditis), intermediate (active granulomatous), and late phase (primarily scar). These pathological processes can affect the myocardial extracellular space volume (ECV) in cardiac sarcoid. We hypothesize that quantitative measurement of ECV using a T1 mapping technique with CMR may yield new insights for the assessment of cardiac
Highlights
Cardiac involvement is a major risk factor for sudden death in patients with systemic sarcoidosis
We hypothesize that quantitative measurement of extracellular space volume (ECV) using a T1 mapping technique with CMR may yield new insights for the assessment of cardiac sarcoid
A short-axis SSFP stack of slices covering the ventricles were acquired, and a pre-contrast modified Look-Locker sequence was performed with 8 time points in a mid-LV level from which a T1 map and average LV myocardium T1 was derived
Summary
Myocardial extracellular space volume in patients with systemic sarcoidosis: quantitative measurement using a T1 mapping technique. Yuesong Yang1*, Anna Zavodni, Idan Roifman, Mohammad I Zia, Meyer Balter, Alexander Dick, Kim A Connelly, Graham A Wright. From 17th Annual SCMR Scientific Sessions New Orleans, LA, USA. From 17th Annual SCMR Scientific Sessions New Orleans, LA, USA. 16-19 January 2014
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