Myiasis Associated with Oral Squamous Cell Carcinoma--A Literature Review.

Sadeq Ali Al-Maweri,Ghadah A Al-Sufyani,Saleem Abdulrab,Bassel Tarakji

doi:10.7314/apjcp.2015.16.12.4997

Abstract

Advanced oral squamous cell carcinoma (SCC) is a possible risk factor for myiasis, a parasitic infestation of vital tissue of humans or other mammals by dipterous larvae (maggots). Oral myiasis is a rare entity, and is mostly associated with various medical and anatomical conditions, such as neglected mandibular fracture, lip incompetence, cerebral palsy, poor oral hygiene, suppurative lesions, and cancerous wounds. Larvae cause itching and irritation due to their crawling movements and can destroy vital tissues, inducing serious or even life-threating hemorrhage. The aim of the present article was to highlight the occurrence of oral myiasis in association with squamous cell carcinoma and also to highlight the treatment and preventive approaches for such cases. A literature search was performed using MEDLINE for articles published in English relating to the occurrence of oral myiasis in oral SCC. Our search revealed 6 reports on myiasis associated with oral SCC. The surgical debridement of infected tissue with the removal of maggots is the treatment of choice in most cases of oral myiasis.

Highlights

The aim of the present article was to highlight the occurrence of oral myiasis in association with squamous cell carcinoma and to highlight the treatment and preventive approaches for such cases
A literature search was performed using MEDLINE for articles published in English relating to the occurrence of oral myiasis in oral squamous cell carcinoma (SCC)
Squamous cell carcinoma (SCC) is the most common type of oral cancer, which forms more than 90% of all oral malignancies (Ferlay et al, 2010; Krishna Rao et al, 2013)

Summary

Introduction

Squamous cell carcinoma (SCC) is the most common type of oral cancer, which forms more than 90% of all oral malignancies (Ferlay et al, 2010; Krishna Rao et al, 2013). Advanced oral cancers can cause significant morbidity and mortality. A rare complication of advanced SCC is myiasis (Gopalakrishnan et al, 2008; Wollina et al, 2014). Primary myiasis is a rare in humans and is caused by biophagous larvae that feed on living tissue. Secondary myiasis is caused by the necrobiophagous flies that feed on necrotic tissue. This is the more common type and attacks patients with necrotic cavity lesions (Antunes et al, 2011). Myiasis is a possible complication of cancerous lesions It has been seen more often in association with cutaneous cancer (Wollina et al, 2014). Many oral myiasis cases associated with squamous cell.

Mandible

Findings

Discussion