Abstract
ObjectivesThis study was aimed to identify the number, shape and distribution of megakaryocytes and to recognize blast cells and its location.Further, to identify presence of fibrosis or increased microvascularity.Also,study correlation between histological findings. MethodsA retrospective was conducted between January 2016 to December 2018 at al-mouwasat university hospital. A total of 44 cases of myeloproliferative disorders using H&E and IHC stains were studied.Chi-square test was performed with descriptive statistics. ResultsMost of our patients were men younger than 75 years of age. 40 was the most prevalent as a median number of megakaryocytes in bone marrow biopsy with normal shape and diffuse pattern, most of biopsies were fibrotic, paratrabecular pattern and absent of hemosiderin deposits that correlate significantly to women patients.Minimal blast cells were more common with diffuse pattern. ConclusionBone marrow biopsy is a useful investigation in myeloproliferative disorders. Evaluation of megakaryopoiesis, fibrosis, and localization of blasts are possible on a bone marrow biopsy.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
