Abstract
A young male developed hearing loss, vertigo, headache and facial palsy. Neurological examination did not show any abnormalities. Two years later, cervical lymphadenopathy, hepatosplenomegaly and atypical lymphocytes in peripheral blood revealed leukemia. At the same time, acquired ichthyosis was observed. Subsequently, neurological abnormalities revealed myelopathy associated with HTLV-1, due to vertical transmission.
Highlights
A young male developed hearing loss, vertigo, headache and facial palsy
Human T cell lymphotrophic virus type 1 (HTLV-1) infection was subsequently identified through the presence of antibodies in the blood, normal protein levels (23mg/dl), mononuclear cell counts in the cerebrospinal fluid (CSF), positive ELISA and Western Blot (WB) for HTLV-1 antibodies in serum and CSF
Hearing loss is not considered to be a common central nervous system (CNS) symptom relating to leukemia[6 10]
Summary
A young male developed hearing loss, vertigo, headache and facial palsy. Neurological examination did not show any abnormalities. Patients with diseases related to HTLV-1 have been evaluated. HTLV-1 is associated with adult T-cell leukemia/lymphoma (ATLL) and myelopathy/tropical spastic paraparesis (HAM/TSP). We report on the case of a young man who developed ATLL and HAM/TSP.
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