Myelomatous Meningitis- a case report and review of literature

Abstract

Multiple Myeloma (MM) is a neoplastic disease of plasma cells characterized by the production of monoclonal immunoglobulin. Myelomatous meningitis is a rare occurrence in multiple myeloma. The signs and symptoms of meningeal myelomatosis are non-specific. The diagnosis of meningeal myelomatosis depends on the demonstration of malignant plasma cells in the cerebrospinal fluid. A combination of radiation therapy and chemotherapy is the usual treatment. We report the case of a woman with myelomatous meningitis. Multiple myeloma was diagnosed by serum protein electrophoresis and bone marrow aspiration.This case and a review of the literature show that clinical manifestations of meningeal myeloma are non-specific .