Abstract
Myeloid derived suppressor cells (MDSC) are a heterogeneous population of cells expressing immature myeloid markers and have been implicated as inhibitors of lymphopoiesis. We determined the number of MDSC in patients with multiple myeloma (MM), the impact of G-CSF on MDSC prior to stem cell collection, the ability of MDSC to induce Treg cells and the impact of MDSC on lymphocyte regeneration post-transplant.
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