Mycotoxins in myelopathies of man

Abstract

Environmental cofactors have been thought to have a role in chronic idiopathic spastic paraparesis (CHISPA), either infected with human T-cell lymphotropic virus type 1 (HTLV-1) (CHISPA +) or not (CHISPA -) 1 Zaninovic V, León-S FE. Fifteen years of follow-up in HTLV-1 positive and HTLV-1 negative spastic paraparesis at Southwestern Colombia, South America. J Neurovirol (in press) Google Scholar , 2 León-S FE, Carpintero M, Bayona J. et al. Un coctel neuropatologico de micotoxinas, retrovirus y paraparesia espastica tropical. UIS-Salud (in press) Google Scholar These patients are usually found in hot and humid regions, most of which have heavy rains, and these conditions allow foods to be polluted by fungi some of which become toxigenic. 1 Zaninovic V, León-S FE. Fifteen years of follow-up in HTLV-1 positive and HTLV-1 negative spastic paraparesis at Southwestern Colombia, South America. J Neurovirol (in press) Google Scholar , 2 León-S FE, Carpintero M, Bayona J. et al. Un coctel neuropatologico de micotoxinas, retrovirus y paraparesia espastica tropical. UIS-Salud (in press) Google Scholar Our chance finding of deoxynivalenol in a patient with CHISPA + 2 León-S FE, Carpintero M, Bayona J. et al. Un coctel neuropatologico de micotoxinas, retrovirus y paraparesia espastica tropical. UIS-Salud (in press) Google Scholar led us to investigate the presence of mycotoxins in patients with CHISPA in southwestern Colombia, an HTLV-1 endemic area. 1 Zaninovic V, León-S FE. Fifteen years of follow-up in HTLV-1 positive and HTLV-1 negative spastic paraparesis at Southwestern Colombia, South America. J Neurovirol (in press) Google Scholar , 2 León-S FE, Carpintero M, Bayona J. et al. Un coctel neuropatologico de micotoxinas, retrovirus y paraparesia espastica tropical. UIS-Salud (in press) Google Scholar