Abstract

I read with interest the article by Resnick et al,1in which the authors attempt to group cases of limited acral cutaneous T-cell lymphoma into a single entity entitled "mycosis fungoides palmaris et plantaris." While this is certainly an admirable goal, I must object to the inclusion of several of their cases under such a designation, including a case report we published.2 Mycosis fungoidesis defined as a neoplastic proliferation of CD4+T-helper cells by most groups studying cutaneous T-cell lymphomas.3-5Our case was that of a cutaneous T-cell lymphoma limited to an extremity for longer than 30 years, which was characterized by CD8+, CD30+, CD4-lymphocytes. This is not an immunophenotype that would ordinarily be seen in mycosis fungoides. In addition, almost half of all reported cases of Woringer-Kolopp disease (pagetoid reticulosis) are CD8+, CD4-T-cell lymphomas. These cases are neoplasms derived from a different population of

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