Mycoses of the skin: Issues of effective therapy

Abstract

A practicing physician always faces a rather difficult task when choosing a topical drug for the treatment of mycoses, while the optimal ratio of efficacy/safety and a wide spectrum of action, including against possible contamination by various pathogens, can be considered a priority factor. Sertaconazole (Zalain) is a highly active broad-spectrum antifungal drug that has fungicidal, antibacterial, anti-inflammatory and antipruritic effects.Material and methods. On an outpatient basis, under our supervision were 25 patients aged 42 to 76 years with a verified diagnosis of foot mycosis, confirmed by microscopic and cultural methods. All patients were prescribed Zalain cream 2 times a day for 4 weeks.Results. After therapy (4 weeks), pathogenic fungi (T. rubrum, T. mentagrophytes var. interdigitale) were not sown in 92% of patients during a cultural study. 8% of patients with no laboratory cure were recommended to continue sertaconazole therapy for 2–4 weeks until complete eradication of pathogenic fungi. Long-term results of observations (6 months) showed no recurrence of the disease in 100% of patients.Conclusions. The high efficacy and safety of Zalain in the treatment of skin mycoses has been proven in numerous studies and confirmed by real clinical practice, which allows us to recommend it for the treatment of patients with this pathology, including in cases of secondary infection and eczematization.