Mycoplasma hyopneumoniae temporal trends of infection and pathological effects in wild boar populations

Abstract

Mycoplasma hyopneumoniae (Mhyo) is the principal etiological agent of enzootic pneumonia (EP), one of the most economically important diseases in the pig production industry worldwide. Although swine and wild boars (Sus scrofa) share susceptibility to Mhyo infection, information regarding the dynamics of Mhyo infections and pathology in wild boars is currently limited. Therefore, the aim of this study was to determine the spatiotemporal dynamics of Mhyo infections in free-living wild boars through serological ELISA testing. Additionally, the presence of EP-like gross lesions and their association with the presence of Mhyo, based on a PCR assay, were assessed. Over a period of 5 years, antibodies against Mhyo were detected in 655 (30.0 %) of the 2,177 analyzed wild boars. A generalized temporal increase of seroprevalence coupled with an increase of mean antibody titers of seropositive individuals was found. Moreover, a similar seroprevalence between age classes associated with higher antibody titers of younger individuals indicated the wild boars were infected during the early stages of their life. Out of 99 lungs tested, 43 showed EP-like lesions and 45 were PCR positive for the presence of Mhyo DNA. The lung lesion scores were related to the sex and age of the wild boars, with young individuals having higher lung scores than others, and there was a positive association with the Mhyo PCR-positive status. The temporal increase of the Mhyo seroprevalence and infection association with EP-like lesions, when coupled with the spreading of wild boar populations, raises concerns on the epidemiological role of this species.