Abstract

Amoxicillin/clavulanate 与肝损伤被联系,主要一个胆汁郁积的模式。当结果通常是良性的时,到肝硬化和死亡的前进被报导了。为有一棵延长的菜的病人的抑制免疫力的治疗的角色是不清楚的。我们报导发展了的一个老病人的案例延长了对 amoxicillin/clavulanate 第二等的胆汁郁积。消失的胆汁管症候群被顺序的肝活体检视证实。病人对泼尼松治疗作出回应,但是不能被断奶离开 corticosteroids,甚至当 azathioprine 被增加时。泼尼松和 azathioprine 的完全的退却由使用 mycophenolate mofetil 是可能的,肌甙单音的磷酸盐脱氢酶禁止者。持续宽恕与低剂量的 mycophenolate mofetil 被维持超过 3 年了。

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