Abstract

Abstract A bacterium which actively lysed Aspergillus fumigatus cell wall was isolated from soil and was identified as belonging to the genus Micrococcus . Under optimal conditions production of the lytic activity paralleled growth; liberation of activity took place during the log phase with maximum activity being obtained at the start of the stationary phase. The lytic activity is produced adaptively in media containing fungal cell wall or colloidal chitin and can be repressed by soluble metabolites in the presence of the inducer. The repression is overcome as the additive is consumed. These findings suggest that production of the mycolytic activity is controlled by an inducer-repressor mechanism.

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