Abstract

We report a case of lymphadenitis caused by Mycobacterium orygis in an immunocompetent person in Stony Brook, New York, USA. Initial real-time PCR assay failed to provide a final subspecies identification within the M. tuberculosis complex, but whole-genome sequencing characterized the isolate as M. orygis.

Highlights

  • We report a case of lymphadenitis caused by Mycobacterium orygis in an immunocompetent person in Stony Brook, New York, USA

  • On the basis of single-nucleotide polymorphism (SNP) and region of difference (RD) analysis, van Ingen et al concluded that these mycobacteria belonged to a phylogenetically distinct lineage of the clonal Mycobacterium tuberculosis (MTB) complex [2]

  • Mycobacterium Growth Indicator Tube (MGIT) system turned positive on day 29, and the isolate was identified as MTB complex by probe hybridization

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Summary

Introduction

We report a case of lymphadenitis caused by Mycobacterium orygis in an immunocompetent person in Stony Brook, New York, USA. Genomic analysis has previously shown that the Mycobacterium tuberculosis (MTB) complex comprises >8 distinct subgroups: M. tuberculosis, M. africanum, M. canettii, M. bovis, M. caprae, M. pinnipedii, M. microti, and M. mungi [1]. We report a case of lymphadenitis caused by M. orygis in an immunocompetent person in Stony Brook, New York, USA.

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