Abstract

To the Editor.— The April issue of theArchiveshas just arrived in South Australia. We read with interest the letter by Drs. Fisher and Lyss (109:571, 1974) relating the combined use of corticosteroid and antituberculous agents in the treatment of anonymous mycobacterial infections. We would like to refer the authors, and your readers, to the study of Barrow and Hewitt ( Br Med J 2:205, 1971) reporting clearing of anonymous mycobacterial infections after treatment with an agent comprised of trimethoprim and sulfamethoxazole. Various members of our practice have since that time used this agent to treat six patients who had Mycobacterium marinum infections and obtained complete resolution in all cases. While we agree with Drs. Fisher and Lyss that treatment with corticosteroid drugs may still be necessary, it is well worth trying the single-drug therapy first.

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