Abstract
In today?s Lancet Jason Evans and colleagues report on a cluster of six patients with tuberculosis caused by Mycobacterium bovis. All were young people born and living in the UK who had documented social links to at least one other person in the cluster. Only one had a history of zoonotic exposure and consumption of unpasteurised dairy products. Five had pulmonary disease; five received BCG vaccine as children including one patient who developed meningitis and died. All M bovis isolates were identical by genotyping. These findings strongly support the authors? contention that several events of person-to-person transmission occurred. Moreover they emphasise that human tuberculosis caused by M bovis persists and might be an underappreciated cause of morbidity and mortality. (excerpt)
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