Abstract
Lymphoreticular tumours, mycobacterial granulomata and responses to antigens in Xenopus toadlets were compared. Lymphoreticular tumours and granulomata differed in histology, development, distribution of mitotic figures, involvement of small lymphocytes, aetiology and transmissibility. Combination experiments provided no evidence that Mycobacterium marinum plays a role in lymphoreticular tumour initiation and development, though, as in some human neoplasms, secondary mycobacterial infection was a feature of advanced tumours.
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