Abstract
Introduction: Myasthenia gravis (MG) is a neuromuscular disorder characterized by weakness and fatigability of skeletal muscles. There is a paucity of data regarding the disease in the state of Andhra Pradesh. Objective: Our aim was to study the clinical profile of patients with myasthenia gravis admitted to government general hospital, Guntur, Andhra Pradesh. Materials and Methods: We studied the cases of 36 myasthenia gravis patients admitted to the government general hospital, Guntur from September 2003 to April 2011. Results: The median age of presentation was 40 years. Male to female ratio was 3:1. The presenting complaint was ptosis in 44.44% of the cases. The other major complaint was lower limb weakness (38.89%). Serum levels of acetylcholine receptor (AChRs) antibodies were more in males (18) than in females (9.22). Conclusion: The median age of presentation and sex ratio matched that with the pattern in India. Ptosis may suggest a possibility of myasthenia gravis to the clinician more easily than any other complaint.
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