Abstract

> I'm a nascent polypeptide chain > > Just emerging from the ribosome. > > Through the cavernous endoplasmic reticulum, > > In search of friends I was asked to roam. > I have been given prior instructions > > That I should assume my natural shape. > > In size, structure, design and architecture > > I'm to become a blueprint, a replica, a remake. > “Don't I have the freedom?” I cried > > “To align the amino acids within me. > > In a manner that I feel convenient, > > After all, I have just now been set free.” > “No!” said some loud voices in unison > > “All of us should obey and fall in line. > > If you want to function in this world, > > Do as we all did and you'll be fine.” > “A globular protein you shall become” > > The master of ceremonies solemnly declared; > > “With an abundance of alpha helices, > > Of beta sheets you'll be spared.” > “Your chaperones are there to guide you > > With them you shall become intimate. > > They'll help you bend, twist and coil, > > Steering you …

Full Text
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