Abstract

Frequent premature ventricular complexes (PVCs) can lead to a reversible cardiomyopathy. Frequent PVCs can also be a marker for the presence of structural heart disease. Both issues need to be addressed when a patient with frequent PVCs is evaluated. The PVC burden needs to be quantified and a predominant PVC morphology, if present, must be identified. This is best done with a 12-lead 48 h Holter monitor. Left ventricular function and dimensions need to be assessed echocardiographically. In the setting of frequent PVCs, there are three important questions that help to guide therapy:

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