Mutual Prediction of Retention Times in a Variety of Operating Modes in Temperature Programmed Gas Chromatography

Abstract

In this paper, a new concept of calibration hold-up time was defined. On the basis of the concept, a novel method was proposed to predict retention times in temperature programmed (isothermal) under constant flow and constant pressure mode each other, and the method also researched in simultaneous pressure and temperature programmed. The prediction results show that average relative errors are 1.33% (0.64%) in temperature programmed (isothermal) under constant pressure mode by using isothermal dates in constant flow mode, and the other way around, average relative errors are 0.62% (−0.62%). For simultaneous pressure and temperature programmed, retention times were predicted by using isothermal dates in constant flow and constant pressure mode, average relative errors are −0.24% and −0.16%; and retention times were predicted by using isothermal dates directly, average relative errors are −0.62%.