Abstract
Cardiac myxomas arise from primitive pluripotent mesenchymal cells within the subendocardium. In autosomal dominant Carney complex, intracardiac myxomas develop in the setting of lentiginosis and endocrinopathy. We previously localized the Carney complex gene defect to human chromosome 17q24. We now demonstrate that mutations in the chromosome 17 PRKAR1α gene encoding …
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